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PEP (post-exposure prophylaxis) means taking antiretroviral medicines (ART) after being potentially exposed to HIV to prevent becoming infected.

PEP should be used only in emergency situations and must be started within 72 hours after a recent possible exposure to HIV. If you think you’ve recently been exposed to HIV during sex or through sharing needles and works to prepare drugs or if you’ve been sexually assaulted, talk to your health care provider or an emergency room doctor about PEP right away.

PEP is any prophylactic (preventive) treatment started immediately after exposure to blood or bodily fluid contaminated with a pathogen (such as a disease-causing virus), in order to prevent infection and the development of disease.

Although multiple diseases can be transmitted from exposure to blood, the most serious infections are hepatitis B virus (HBV), hepatitis C virus (HCV), and for hiv. Fortunately, the risk of acquiring any of these infections is low.

In order to be exposed to a blood borne pathogen, you must have contact with blood, a visibly bloody fluid (i.e., phlegm or urine containing blood), or another bodily fluid (i.e., semen or vaginal secretions) that contain an infectious organism (virus or bacteria). The blood or fluid must come in direct contact with some part of your body. A virus can enter your body through the bloodstream, open skin, or mucous membranes, which include the eye, mouth, or genitals. Contact with skin that is intact (without new cuts, scrapes, or rashes) poses no risk of infection.
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